We introduce the class of instantly independent stochastic processes, which serve as the anticipating counterpart of adapted stochastic processes in the Ito theory. This leads to a new stochastic integral with integrands being sums of product of adapted and instantly independent stochastic processes. The crucial idea, in forming Riemann-like sums, is to use the left endpoints of subintervals to evaluate the adapted factors and to use the right endpoints to evaluate the instantly independent factors. The new stochastic integral has many advantages than the white noise methods, e.g., it has a probabilistic interpretation and is connected to the underlying filtration. Moreover, by using this new stochastic integral, we can treat a multiple Wiener-Ito integral as a true iterated stochastic integral. We also obtain extensions of Ito's formula and study stochastic differential equation with an anticipating initial condition or integrands being anticipating.